BALDWIN LAB :: Lineberger Comprehensive Cancer Center

The Baldwin Lab is in the Lineberger Comprehensive Cancer Center,  an NCI designated Cancer Center associated with the UNC School of Medicine the University of North Carolina at Chapel Hill.
Research in our lab primarily focuses on the molecular biology of the transcription factor NF-kB as it relates to cancer, apoptosis, and molecular signalling. NF-kB serves as the prototype of the inducible transcription factor because it is found in the cytoplasm of most cells in association with an inhibitor, known as IkB, and since its movement into the nucleus can be induced by various physiological stimuli. Once in the nucleus, NF-kB regulates transcription of a wide range of critical genes including many involved in cell growth control and in immune and inflammatory responses. In addition, NF-kB is a critical regulator of HIV gene expression.

UNC Lineberger Comprehensive Cancer Center
CB# 7295
Chapel Hill, NC 27599

tel: 919.966.3884, 919.966.6928

© 2006 UNC Lineberger Comprehensive Cancer Center. Revised March 2006.