New Brain Metastases Specialty Clinic


The newest multidisciplinary clinic at UNC focuses on the unique challenges of brain metastases. The goal of the Brain Metastases Specialty Clinic is to improve outcomes, enhance quality of life, and offer new therapeutic strategies for patients with brain metastases. We are focusing this clinic on breast cancer brain metastases with plans to expand our efforts to other tumors (lung, melanoma) in the near future.


All patients receive a comprehensive multidisciplinary assessment by our team of medical and radiation oncologists, neurosurgeons, neuroradiologists and supportive care staff. The initial step in our evaluation of these patients occurs in our Brain Tumor Board, followed by simultaneous clinic visits by Drs. Carey Anders (Medical Oncology), Timothy Zagar (Radiation Oncology) and Matthew Ewend (Neurosurgery) in the N.C. Cancer Hospital.


For patient referrals, call Lauria Themes at 919-843-8869, email her, or fax 919-843-5016.


View website for more information.


Ongoing Clinical Trial Evaluating New Vaccine Therapy for Breast Cancer

The UNC Breast Cancer Program in concert with the UNC Lineberger Immunotherapy program is recruiting patients with metastatic breast cancer to enter an ongoing clinical trial evaluating a new vaccine therapy for breast cancer combined with chemotherapy and trastuzumab.  


This therapy combines a dendritic cell vaccination prepared from each patient's own dendritic cells and pulsed with two different parts of the HER-2/neu oncogene, given with vinorelbine and trastuzumab. The dendritic cell vaccine is given by an injection under the skin. The vaccine and the chemotherapy are given once every two weeks for six treatments. This trial, which is sponsored by the Susan G. Komen for the Cure Foundation, is for patients with HER 2 overexpressing metastatic breast cancer whose cancer has progressed after at least one chemotherapy treatment and who express the HLA protein HLA-A0201 for which they are prescreened. Both the vinorelbine and trastuzumab can be given locally on the day prior to vaccination each cycle. 


Thus far, encouraging results have been found for overall survival for those patients who mount an immune response after vaccination. 


If you are interested in learning more about the study or would like to refer a patient, call Rachel Phipps, RN, study coordinator, at 919-843-7197 or email her.




The Brain Metastases Specialty Clinic currently sees Breast cancer patients with brain metastases at any point in their course. The clinic is held on Wednesday mornings in the N. C. Cancer Hospital's Radiation Oncology Clinic. View website.


New Geriatric Oncology Specialty Clinic


We welcome our new  Geriatric Oncology clinic. The goal of the Geriatric Oncology Clinic is to provide the referring clinician with information focused on personalizing treatment for older cancer patients who are candidates for chemotherapy, but for whom there are concerns about treatment tolerance and potential benefits.


The Geriatric Oncology clinic is held on Mondays at the N.C. Cancer Hospital Outpatient Clinic. Whenever possible, we will accommodate requests for consultations at other times. We are accepting referrals for solid tumor and hematological malignancy patients aged 70 and over.



All patients will receive a Comprehensive Geriatric Assessment which is the cornerstone evaluation of older adults. The assessment aims to detect functional, cognitive and psychosocial impairments that can increase the risk of adverse outcomes during cancer treatment. It includes a detailed review of comorbidities and medications to evaluate potential adverse drug reactions and polypharmacy risk.


To refer a patient, call (toll-free) 1-866-869-1856
or 919-843-8442 or fax 919-966-0393.


View brochure for more information.


More Information

For more information about UNC Breast Center clinical trials, call: 919-966-4432.


For more information about the UNC Breast Center, including how to refer a patient, visit the center's website.

UNC Lineberger    N.C. Cancer Hospital    Clinical Trials     Clinical Programs    Comprehensive Cancer Support


For questions about all clinical trials at UNC (including those at UNC that are also offered at other sites), contact the UNC Lineberger protocol office at 919-966-4432 or (toll-free) 1-877-668-0683.


To make an appointment at the N.C. Cancer Hospital for one of your patients, visit our web page for referring physicians. You may also contact the Carolina Consultation Center at 1-800-862-6264.