Clinical Interests
My clinical research interests relate to benign and malignant hematologic disease.

Research Interests
Research in my laboratory is focused on gaining an understanding the mechanisms that govern lineage commitment and stem cell pluripotency in physiologic and pathologic settings. Specifically, we are interested in defining how translational control of gene expression regulates these events. Mechanisms of murine embryonic stem cell differentiation, cancer stem cell differentiation and hematopoietic lineage commitment are examined in studies to define the events and mechanisms that regulate the translation of critical transcripts. Past trainees in my laboratory include Drs. Shahin Rafii (Weill Cornell, HHMI), Erik E. Griffin (CalTech) and Enrique Mesri (Univ. Miami, Miller School of Medicine).

Recent Accomplishments and Honors
1985 New York Heart Association Clinical Investigatorship Award
1985 NIH Clinical Investigator Award
1986 Louis B. Sklarow Memorial Trust Award for Medical Research
1988 Andrew W. Mellon Teacher-Scientist Award
1988 Charles A. Frueauff Foundation Award
1989 Andrew W. Mellon Teacher-Scientist Award
1989 Stratton Foundation Award
1990 NIH Research Career Development Award
1995 American Society for Clinical Investigation

Training
June 1974 B.A. Degree from Swarthmore College
June 1979 M.D. Degree from Thomas Jefferson Medical School, Thomas Jefferson University, Philadelphia, Pa.

E-mail: ASCHA@ecu.edu
Telephone: 212-746-2072
FAX: 212-746-8866
Address: Brody School of Medicine Greenville, NC 27834

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