Research Interests
Dr. Gabriel's area of research is fluid dynamics and coagulation. Clinically, Dr. Gabriel has focused on the use of autologous PBSC transplants for multiple myeloma and has opened an outpatient transplant study combining mitoxantrone and melphalan. He has also recently developed a series of laboratory studies that are designed to investigate the ability of markers of endothelial cell damage to predict for the occurrence of veno-occlusive disease and other endothelial based tissue injuries such as alveolar hemorrhage.

Publications
Gabriel, D.G.: A perspective on the role of coagulation in the development of the multi-organ failure syndrome. Current Concepts in Pediatric Critical Care, 1997, Chapter 5, pp. 57-72, 1997.

Li., X., and Gabriel, D.A.: The physical exchange of FVIII between von Willebrand factor and activated platelets and the effect of the FVIII B-domain on platelet binding. Biochemistry, 36:10760-10767, 1997.

Freskgrd, P.O., Peterson, L.C., Gabriel, D.A., Li, X., and Persson, E. The stability of FVIIa - Biophysical studies of thermal and guanidine hydrochloride induced denaturation. Biochemistry. 37: 7203-7212, (1998).

Melton, L.G., Dehmer, G., Muga, K. and Gabriel, D.A.: Alterations in fibrin detected in coronary sinus blood after coronary angiography with non-ionic contrast agent. Am. J. Cardiology, 82: 295-298, (1998).

Johnson, C.S., Jr. and Gabriel, D.A.: Dynamic Light Scattering. Dover Publications: 1995.

E-mail: Laser@med.unc.edu
Telephone: (919) 966-4431
Address: 260 MacNider, CB# 7305 Chapel Hill, NC

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