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Recent Publications Miller, E., J. Smith, M. Lichtinger, L. Wang and
L. Su (2003) Activation of the signal transducer and activator of transcription 1 signaling pathway in thymocytes from HIV-1-infected human thymus. AIDS. 17:1269-1277 V. M. Coffield, Q. Jiang and
L. Su (2003) A Novel Genetic Approach to Inactivating Chemokine Receptors by a Modified Viral Protein. Nat. Biotechnol. 21(11):1321-1327 Gebuhr, T.*, G. Kovalev*, S. Bultman, V. Godfrey,
L. Su and T. Magnuson (2003) The role of Brg1, a catalytic subunit of mammalian chromatin remodeling complexes, in T cell development. J. Exp. Med. 198:1937-1949 (*co-first authorship) Meissner, E.G. , K. Duus, F. Gao, X. Yu and
L. Su (2003) Characterization of a thymus-tropic HIV-1 isolate from a rapid progressor: role of the envelope gene. Virology. 328(1):74-88 V. M. Coffield, W. Helms, Q. Jiang and
L. Su (2003) G?13 mediates a signal that is critical for early thymocyte proliferation and survival. J. Exp. Med. 328(10):1315-1324 Krishnamurthy J, Torrice C, Ramsey MR, Kovalev GI, Al-Regaiey K,
Su L, Sharpless NE (2004) Ink4a/Arf expression is a biomarker of aging. J Clin. Invest. 114(9):1299-1307 Meissner, E.G., V. M. Coffield and
L. Su (2005) Thymic pathogenicity of an HIV-1 envelope is associated with increased CXCR4 binding efficiency and V5-gp41-dependent activity, but notV1/V2-associated CD4 binding efficiency and viral entry. Virology. 336:184-197 Okada, Y., Q. Feng, Y. Lin, Q. Jiang, Y. Li, V. M. Coffield,
L. Su, G. Xu and Y. Zhang (2005) hDOCT1L links histone methylation to leukemogenesis. Cell. (121):167-178 Wysocki CA, Jiang Q, Panoskaltsis-Mortari A, Taylor PA, McKinnon KP,
Su L, Blazar BR, Serody JS (2005) Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease. Blood. 106(9):3300-3307 Chang X, Gao JX, Jiang Q, Wen J, Seifers N,
Su L, Godfrey VL, Zuo T, Zheng P, Liu Y (2005) The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis. J. Exp. Med. 202(8):1141-1151 Williams KL, Lich JD, Duncan JA, Reed W, Rallabhandi P, Moore C, Kurtz S, Coffield VM, Accavitti-Loper MA,
Su L, Vogel SN, Braunstein M, Ting JP (2005)The CATERPILLER Protein Monarch-1 Is an Antagonist of Toll-like Receptor-, Tumor Necrosis Factor {alpha}-, and Mycobacterium tuberculosis-induced Pro-inflammatory Signals. J. Biol. Chem. 280(48):39914-39924 Kovalev, G., T. Simon, V. Coffield, D. Franklin, and
L. Su (2006) Control of Thymocyte Proliferation and Thymus Organ Size by CDK Inhibitors p18Ink4c and p27Kip1. J. Stem Cells 1. (2):97-108 Qi, J., H. Su, G. Knudsen, W. Helms, and
L. Su (2006) Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP. BMC Immunology. 7(1):6 Okada, Y., Q. Jiang, Margot Lemieux, Lucie Jeannotte,
L. Su, and Y. Zhang (2006) Leukaemic transformation by CALM–AF10 involves in upregulation of Hoxa5 by hDOT1L. Nat Cell Biol. 8(9):1017-1024 Meissner, E.G., L. Zhang, S. Jiang and
L. Su (2006) Envelope/Fusion-dependent depletion of HIV+ thymocytes is correlated with induction of apoptosis. J. Virol. (22):11019-11030 Loomis, R., D. Holmes, A. Elms, R., Solski, P., C. Der, and
L. Su (2006) Citron, a RhoA Effector, Enhances HIV-1 Viral Release by Modulating Exocytosis. Traffic. 7:1643-1653 Zhang, L., G. I. Kovalev, and
L. Su (2006) HIV-1 Infection and Pathogenesis In A Novel Humanized Mouse Model. Blood. 109(7):2978-2981 Holmes, D., G. Knudsen, S. Mackey, and
L. Su (2006) FoxP3 Enhances HIV-1 Gene Expression by Modulating NFkB Occupancy at the LTR in Human T Cells. J. Biol. Chem. 282(22):15973-80 Qi, J., V. M. Coffield, M. Kondo and
L. Su (2007) TSLP stimulates expansion of thymocyte progenitors and thymopoiesis. BMC Immunology. (in press) Helms, W., M. Townsend, N. Clipstone, and
L. Su (2007) Modulation of NFAT-Dependent Gene Expression by RhoA. J. Leuk. Biol. (Volume 82, August 2007) Laakso, Meg M., Fang-Hua Lee, Beth Haggarty, Caroline Agrawal, Katrina M. McGeehan, Mark Biscone, George J. Leslie, Josephine Romano, Andrea P.O. Jordan, Eric G. Meissner,
Lishan Su, James A. Hoxie, and Robert W. Doms (2007) V3 Loop Truncations in HIV-1 Envelope Impart Resistance to Coreceptor Inhibitors and Enhanced Sensitivity to Neutralizing Antibodies. PLoS Pathog. 3(8): e117 doi:10.1371/journal.ppat.0030117
Nordone, S.K., Ignacio. G.A., Golenbock, D.T., Latz, E., Sempowski, G.D.,
Su, L., Li, L., Dean, G.A. (2007) Toll-like receptor 4 ligation on HIV-1 infected cells does not induce cytokine or virus production. AIDS Res and Hum Retrovir. (in press)
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