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  8. Franklin, D. F. and Xiong, Y. (1996). Induction of CDK inhibitor p18 and its predominant association with CDK4 and CDK6 during myogenic differentiation. Molecular Biology of the Cell 7:1587-1599. Read Abstract

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 10. Phelps, D., Hsiao, K-M., Li, Y., Hu, N., Franklin , D. S., Westphal, E.,Lee, E., and Xiong, Y. (1998). Coupled transcriptional and translational control of CDK inhibitor p18^INK4cs expression during myogenesis. Molecular and Cellular Biology 18:2334-2343. Read Article

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 12. Zhang, Y., Xiong, Y., and Yarbrough, W. G. (1998). ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 92:725-734. Read Article

 13. Michel, J., and Xiong, Y. (1998) Human cullin 1, but not other cullin family members, selectively interacts with SKP1 to form a complex withSKP2 and cyclin A. Cell Growth Differentiation 9:439-445. Read Article

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 19. Ohta, T., Michel, J., and Xiong, Y. (1999). Association with cullin partners protects ROC proteins from proteasome-dependent degradation. Oncogene 18:6756-6766. Read Article 

 20. Franklin, D.S., Godfrey, V.L., OˇŻBrien, D.A., Deng, C., and Xiong, Y. (2000). Functional collaboration between different CDK inhibitors suppress tumor growth with distinct tissue specificity. Molecular and Cellular Biology 20:6147-58. Read Article

 21. Furukawa, M., Zhang, Y., McCarville, J., Ohta, T., and Xiong, Y. (2000). The CUL1 C-terminal sequence and ROC1 promote nuclear accumulation and NEDD8 modification of CUL1, resulting in efficient ubiquitin ligase activity. Molecular and Cellular Biology 20:8185-8197. Read Article

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 25. Yarbrough, W.G., Bessho, M., Zanation, A., Bisi, J.E., Xiong, Y. (2002). Human tumor suppressor ARF impedes S-phase progression independent of p53. Cancer Research 62:1171-1177. Read Article

 26. Liu, J., Furukawa, M., Matsumoto,T., Xiong, Y. (2002). NEDD8 modification ofCUL1 dissociates p120^CAND1, an inhibitor of CUL1-SKP1 binding and SCF ligases. Molecular Cell 10:1511-1518. Read Article

 27. Bai, F., Pei , X.H., Godfrey, V.L., Xiong, Y. (2003). Haploinsufficiency of p18^INK4csensitizes mice to carcinogen-induced tumorigenesis. Molecular and Cellular Biology 23:1269-1277. Read Article

 28. Shumway, S.D. , Li Y., Xiong, Y. (2003). 14-3-3 beta binds to and negatively regulates the tuberous sclerosis complex 2 (TSC2) tumor suppressor gene product, tuberin. Journal of Biological Chemistry 278:2089-2092. Read Article

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 30. Furukawa, M., He, Y.J., Borchers, C., Xiong, Y. (2003). Targeting protein ubiquitination by BTB-cullin 3-Roc1 ubiquitin ligases. Nature Cell Biology 5:1001-1007. Read Article

 31. Zhang, Y, Whitewolf, G., Allio, T., Jin, A., Bhat, K., Burkhart, W., Xiong, Y. (2003). Ribosomal protein L11 binds to and negatively regulates oncoproteins HDM2. Molecular and Cellular Biology 23:8902-8912. Read Article

 32. Feng, S., Shen Y., Sullivan, J.A., Rubio, V., Xiong, Y., Sun, T.P., Deng, X.W. (2004) The Arabidopsis thaliana CAND1, an unmodified CUL1 interacting protein, is involved in multiple development pathways controlled by ubiquitin/proteasome-mediated protein degradation. Plant Cell 16:1870-1882. Read Article

 33. Pei, XH, Bai, F., Tsutsui, T., Kiyokawa, H., Xiong, Y. (2004) Genetic evidence for functional dependency of p18^Ink4c on CDK4. Molecular and Cellular Biology 24:6653-6664. Read Article

 34. Goldenberg, SL, Cascio, TC, Shumway, SD , Garbutt, KC, Liu, J, Xiong, Y., Zheng, N. (2004) Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multi-subunit cullin-based ubiquitin ligases. Cell 119:517-528. Read Article

 35. Hu, J., McCall, C.M., Ohta, T., Xiong, Y. (2004) Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage. Nature Cell Biology 6:1003-1010. Read Article

 36. Furukawa, M., Xiong, Y. (2005) BTB protein Keap1 targets the antioxidant transcription factor Nrf2 for ubiquitination by the cullin 3-Roc1 ligase. Molecular and Cellular Biology 25:162-171. Read Article

 37. Karnik, S.K., Hughes, C.M., Gu, X., Rozenblatt-Rosen, O., McLean, G.W., Xiong, Y., Meyerson, M., Kim, S.K. (2005) Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27^Kip1 and p18^INK4C. Proceedings of the National Academy of Science 102:14659-64. 24:6653-6664. Read Article

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 39. Hu, J., Xiong, Y. (2006) An evolutionarily-conserved function of PCNA for Cdt1 degradation by the Cul4-Ddb1 ubiquitin ligase in response to DNA damage. Journal of Biological Chemistry 281:3753-3756. Read Article

 40. Andrews, P., He, Y.J., Xiong, Y. (2006) Cytoplasmic localized ubiquitin ligase cullin 7 binds to p53 and promotes cell growth by antagonizing p53 function. Oncogene 25(33):4534-48. Read Article

 41. Wang, H., Zhai, L., Xu, J., Joo, H.Y., Jackson, S., Erdjument-Bromage, H., Tempst, P., Xiong, Y., Zhang, Y. (2006) Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. Molecular Cell 22:383-94. Read Article

 42. Bai, F., Pei, X.H., Pandolfi, P.P. , Xiong Y. (2006) p18^Ink4c and Pten constrain a positive regulatory loop between cell growth and cell cycle control. Molecular and Cellular Biology 26:4564-4576. Read Article

 43. He, Y. J., McCall, C.M., Zeng, Y., Xiong, Y. (2006) DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4–ROC1 ubiquitin ligases. Genes & Development 20:2949-2954. Read Article

 44. Kotake, Y., Cao, R., Viatour, P., Sage, J., Zhang, Y., Xiong, Y. (2007) pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4a tumor suppressor gene. Genes & Development 21:49-54. Read Article 

 45. Bai, F., Pei, X.H., Nishikawa, T., Smith, M.D., Xiong, Y. (2007) p18Ink4c, but Not p27Kip1, Collaborates with Men1 To Suppress Neuroendocrine Organ Tumors. Molecular and Cellular Biology 27:1495-504. Read Article 

 46. Pei, X.H., Bai, F., Smith, M.D., Xiong, Y. (2007) p18^Ink4c Collaborates with Men1 to Constrain Lung Stem Cell Expansion and Suppress Non–Small-Cell Lung Cancers. Cancer Research 67:3162-3170. Read Article 

 47. Ramsey, M.R., Krishnamurthy, J., Pei, X.H., Torrice, C., Lin, W., Carrasco, D.R., Ligon, K.L., Xiong, Y., and Sharpless, N.E. (2007) Expression of p16^Ink4a Compensates for p18^Ink4c Loss in Cyclin-Dependent Kinase 4/6–Dependent Tumors and Tissues. Cancer Research 67:4732-4741. Read Article 

 48. Lee, J.H., Terzaghi, W., Gusmaroli, G., Charron, J.B., Yoon, H.J., Chen, H., He, Y.J., Xiong, Y., Deng, X.W. (2008) Characterization of Arabidopsis and Rice DWD Proteins and Their Roles as Substrate Receptors for CUL4-RING E3 Ubiquitin Ligases. Plant Cell 28(7):2426-36. Read Article 

 49. Lei, Q.Y., Zhang, H., Zhao, B., Zha, Z.Y., Bai, F., Pei, X.H., Zhao, S., Xiong, Y., Guan, K.L. (2008) TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway. Molecular and Cellular Biology 20(1):152-67. Read Article 

 50. Hu, J., Zacharek, S., He, Y.J., Lee, H., Shumway, S., Duronio, R.J., Xiong, Y. (2008) WD40 Protein FBW5 Promotes Ubiquitination of Tumor Suppressor TSC2 by DDB1-CUL4-ROC1 Ligase. Genes & Development 22(7):866. Read Article 

 51. Zhang, Y., Feng, S., Chen, F., Chen, H., Wang, J., McCall, C., Xiong Y., Deng, X.W. (2008) Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 Forms a Nuclear E3 Ubiquitin Ligase with DDB1 and CUL4 That Is Involved in Multiple Plant Developmental Processes. The Plant Cell 20(6):1437-1455. Read Article 

 52. McCall, C.M., Miliani de Marval, P.L., Chastain, P.D. II, Jackson, S.C., He, Y.J., Kotake, Y., Cook, J.G., Xiong, Y. (2008) HIV-1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development. Molecular and Cellular Biology Epub ahead of print. Read Article